منابع مشابه
Ocular melanoma.
The eye is the second most common site for primary melanoma after the skin. An ophthalmologic evaluation should be an integral aspect of melanoma screening that is often not even considered by nonophthalmologists. Delays or failures to make an accurate and early diagnosis can have grave consequences. Early recognition and diagnosis, before the tumor has progressed into an advanced process with ...
متن کاملEditorial: Prognosis in ocular melanoma
There is no doubt that the survival prospects of individuals who develop uveal melanoma are better when this tumour arises in the iris than when it does so in the ciliary body or the choroid. The relatively benign behaviour of iris melanomas in comparison with the behaviour of those which develop at other sites within the uveal tract may be explained by special features of their clinical presen...
متن کاملGermline BAP1 Inactivation Is Preferentially Associated with Metastatic Ocular Melanoma and Cutaneous-Ocular Melanoma Families
BACKGROUND BAP1 has been shown to be a target of both somatic alteration in high-risk ocular melanomas (OM) and germline inactivation in a few individuals from cancer-prone families. These findings suggest that constitutional BAP1 changes may predispose individuals to metastatic OM and that familial permeation of deleterious alleles could delineate a new cancer syndrome. DESIGN To characteriz...
متن کاملCharacterisation of ocular melanoma with cutaneous melanoma antibodies.
It can be difficult to distinguish between various forms of pale intraocular tumour, and in particular between an amelanotic malignant melanoma, a choroidal haemangioma, and a solitary metastasis. If a monoclonal antibody specific for melanoma could be identified, it might be radiolabelled to provide a scanning technique which could distinguish between an ocular melanoma and a similar lesion. T...
متن کاملMetastatic melanoma after 23 years of primary ocular melanoma
We describe a case of 52-year-old man who presented with an episode of tonic-clonic seizures. He had right ocular melanoma 23 years ago with subsequent enucleation which was the standard treatment at that time. CT scans of the brain and of the thorax-abdomen-pelvis revealed widespread metastatic lesions in the brain, lung and liver. Further investigations including bronchoscopy with cytopatholo...
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ژورنال
عنوان ژورنال: Saudi Journal of Ophthalmology
سال: 2012
ISSN: 1319-4534
DOI: 10.1016/j.sjopt.2012.02.004